SK-II Genoptics Ultraura Essence in Beauty: NA. SK-II Genoptics Ultraura Essence in Beauty: NA. A brightening serum that visibly transforms skin with regular use as dullness is holistically reduced and skin tone is brightened.. Suitable for all skin types Targets dark spots, dullness, and uneven texture. Cruelty-free GenOptics Ultraura Essence Serum makes skin look brighter right after application. Free of phthalates, sulfates, soy, and gluten. 50 ml. Release a dropper-full amount of serum into your palm. Apply evenly onto your face by dotting on the forehead, both cheeks, and chin.. Add a few extra drops to areas you're concerned about, and gently massage into skin. Complete the treatment with light tapping for better penetration.. Use daily, in the morning and again in the evening, for best results.. SKTW-WU53. 381519084355. In the 1970s, SK-II scientists began a fervent quest to uncover a skincare ingredient that would make beautiful skin a reality. Researching a myriad of possibilities ranging from Chinese herbs to hot spring water - the secret they were looking for eluded them for a long time. It was only by a chance encounter that the scientists observed the soft and youthful hands of aged sake brewers. The astounding sight of the wrinkled faces of aged sake brewers contrasting their soft youthful hands remained seared in the memories of the SK-II scientists. Back in the confines of the laboratory, they surmised that the secret must lie in the yeast that the brewers' hands were in constant contact with during the sake fermentation process. And that is how an exhaustive research of over 350 yeast strains began. Poring over even the smallest singular detail, the scientists spent over five years isolating the single yeast strain that held the secret to crystal clear skin. It was the birth of a miracle, a beauty revolution that would soon come to be known as PITERA.