BeautyBio R45 The Reversal 3-Phase Retinol Cream System is a patented advanced three-phase system that helps reduce the appearance of fine lines and wrinkles. A proprietary mixture of vitamin A and peptides helps improve the appearance of wrinkles, skin tone evenness, and pores. The wrinkle-filler alternative optimizes the epidural layers of the skin and assists with natural cell turnover. Titration therapy helps mitigate the traditional side effects associated with highly active Vitamin A products. The concentration of ingredients increases from Phase 1 through Phase 3. How do I use it: Use nightly for 45 days, twice yearly. Use Phase 1 for two weeks, Phase 2 for the following two weeks, and Phase 3 for the final two weeks. Cleanse with a gentle cleanser. Use a pump of Phase 1A and a pump of Phase 1B nightly. Once two weeks have elapsed, switch over to Phase 2, and repeat process until finished with Phase 3. Results are cumulative. Do not start with Phase 3. Individual results may vary. Avoid direct eye contact. Component is recyclable. From BeautyBio. Includes: